Spanning Tree Protocol (STP) is a Layer 2 loop prevention mechanism that ensures a loop-free topology in Ethernet networks by selectively blocking redundant paths while maintaining network connectivity and providing automatic failover capabilities. It supports multiple implementations including Per-VLAN Spanning Tree Plus (PVST+), Rapid Per-VLAN Spanning Tree Plus (RPVST+), and Multiple Spanning Tree (MST) protocol, each offering different approaches to VLAN-aware loop prevention and convergence optimization. Spanning Tree configuration includes features like PortFast for edge ports, BPDU Guard for security, root bridge selection, and path cost manipulation to optimize network topology and ensure rapid recovery from link failures while preventing broadcast storms and network instability.